Houston Texans running back Joe Mixon is expected to miss multiple weeks of training camp due to a foot injury, NFL Network reported Saturday.

He will be re-evaluated later this summer to see if he’ll be ready for the Sept. 7 season opener against the host Los Angeles Rams, per the report.

Mixon, who was placed on the non-football injury list Wednesday, has a $7 million base salary in 2025 — $4 million of which is guaranteed.

A Pro Bowl selection during his first season in Houston, Mixon rushed for 1,016 yards and 11 touchdowns in 14 games (all starts) in 2024.

Mixon, 29, has rushed for 7,428 yards and 60 touchdowns in 111 career games (102 starts) with the Cincinnati Bengals (2017-23) and Texans. He earned his second Pro Bowl selection in 2024.

Houston’s backfield also includes offseason additions Nick Chubb, Dare Ogunbowale and rookie Woody Marks, among others. Marks was selected by Houston in the fourth round of the 2025 NFL Draft out of Southern California.

Fellow running backs Dameon Pierce and J.J. Taylor also are on the physically unable to perform list.